Fig. 7.
Kupffer cell elimination reduced hepatic ischemia–reperfusion (IR)–induced H2O2 production. (A) Immunohistochemical staining of liver sections with the anti-mouse CD68 antibody after Clophosome-A treatment (180 μl per mouse, intravenous; three times at 3-day intervals). Each arrow represents a CD68-positive cell; original magnification: ×100. (B) IR-induced H2O2 production in the liver was significantly reduced in mice treated with Clophosome-A. n = 7 per group; *P < 0.05 and **P < 0.01.