Fig. 5.
Dendritic architecture is changed in the perirhinal cortex of fracture/cast mice. Cast/fracture mice display increased dendritic complexity in the perirhinal cortex as shown by the mean number of intersections of dendrite branches with consecutive 5-μm-spaced concentric Sholl rings (A) and by calculating the area under the curve (AUC) for these two curves (A, inset). In addition, the fracture group has a significantly greater number of secondary nodes compared with control (B) and a greater average of total dendritic length (C). No differences were observed in average soma area (D), total number of neurons (E), or dendritic spine density (F, G). Scale bar = 1 μm. *P < 0.05, **P < 0.01. n = 5 (control) and n = 7 (fracture/cast). Errors bars = SEM. Red arrows point to dendritic spines.