Fig. 2.
Effect of different concentrations of tissue plasminogen activator (t-PA) on the EXTEM clotting time (CT; A), EXTEM clot formation time (CFT; B), and EXTEM maximum clot firmness (MCF; C) in the absence (control) or presence of the antifibrinolytic aprotinin (APTEM). D shows a dose-dependent effect of t-PA on the FIBTEM MCF. The effects of incremental concentrations of t-PA on the level of platelet aggregation expressed as area under the curve (AUC) are depicted in E. Data represent mean ± SD.