(A) Box-whisker plot of night-time sleep architecture with and without dexmedetomidine infusion. Data pertain to 12 patients. (B) Individual percentage of total sleep time of stages 1 and 2 of sleep with and without dexmedetomidine infusion. Each color denotes an individual patient. *Significantly different from the corresponding sleep stage without dexmedetomidine. REM = rapid eye movement sleep; SWS = slow wave sleep (N3); TST = total sleep time.