Fig. 10.
Schematic representation of the modulation of serine racemase (SR) expression functioning via mammalian target of rapamycin (mTOR) and extracellular signal–regulated kinase (ERK) pathways. HNK = (2S,6S)-hydroxynorketamine; Ket = (R,S)-ketamine; mTORC1 = mTOR complex 1; mTORC2 = mTOR complex 2; nAchR = nicotinic acetylcholine receptor; NorKet = (R,S)-norketamine.

Schematic representation of the modulation of serine racemase (SR) expression functioning via mammalian target of rapamycin (mTOR) and extracellular signal–regulated kinase (ERK) pathways. HNK = (2S,6S)-hydroxynorketamine; Ket = (R,S)-ketamine; mTORC1 = mTOR complex 1; mTORC2 = mTOR complex 2; nAchR = nicotinic acetylcholine receptor; NorKet = (R,S)-norketamine.

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