Fig. 1.
(A) Hematocrit in percent, before and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from seven animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure according to Bonferroni method was conducted. PTime < 0.0001; PGroup: 0.909; PTime × Group: 0.134; Ppost hoc < 0.0001. (B) Colloid osmotic pressure in plasma (COPp) in mmHg, before and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from seven animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure, according to Bonferroni method, was conducted. PTime < 0.0001; PGroup: 0.267; PTime × Group: 0.026; PPost hoc < 0.0001. A two-sample t test was performed to compare the two groups at time point 120 min. Between-group difference (pb) at time 120 min is reported (pb = 0.06). (C) Colloid osmotic pressure in interstitial fluid (COPi) in mmHg, before, and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from six animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure, according to Bonferroni method, was conducted. PTime < 0.029; PGroup: 0.178; PTime × Group: 0.041; Ppost hoc < 0.209. A two-sample t test was performed to compare the two groups at time point 60 min. Between-group difference (pb) at time 60 min is reported (pb = 0.009).

(A) Hematocrit in percent, before and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from seven animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure according to Bonferroni method was conducted. PTime < 0.0001; PGroup: 0.909; PTime × Group: 0.134; Ppost hoc < 0.0001. (B) Colloid osmotic pressure in plasma (COPp) in mmHg, before and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from seven animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure, according to Bonferroni method, was conducted. PTime < 0.0001; PGroup: 0.267; PTime × Group: 0.026; PPost hoc < 0.0001. A two-sample t test was performed to compare the two groups at time point 120 min. Between-group difference (pb) at time 120 min is reported (pb = 0.06). (C) Colloid osmotic pressure in interstitial fluid (COPi) in mmHg, before, and during 120 min of cardiopulmonary bypass. Closed circles: isoflurane-group (I-group); open circles: propofol-group (P-group). The data represent the mean values with SD from six animals in each group. A repeated measure ANOVA with one within-factor (time) and one between-factor (group) was used to analyze each of the variables. If the within-factor P value (PTime) was less than 0.05, a multiple comparison procedure, according to Bonferroni method, was conducted. PTime < 0.029; PGroup: 0.178; PTime × Group: 0.041; Ppost hoc < 0.209. A two-sample t test was performed to compare the two groups at time point 60 min. Between-group difference (pb) at time 60 min is reported (pb = 0.009).

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