Fig. 6.
Biochemical markers of proteasome activity and autophagy. (A) Atrogin, (B) muscle ring finger protein (MURF) 1, (C) LCII/LCI ratio as indicator of autophagic activation. Values represent the mean percentage change ± SD. CON = unventilated control animals; LC = microtubule-associated protein 1A/1B-light chain 3; NPV = negative pressure ventilation; PPV = positive pressure ventilation. *P < 0.05 versus CON, n = 8 each.