Fig. 3.
Association results between the studied catechol-O-methyltransferase (COMT) gene single nucleotide polymorphisms (SNPs) and two cold pressure pain phenotypes (pain intensity at 15 s and cold withdrawal time). Results are based on the dominant model, and both uncorrected (empirical) and experimental-wise corrected (by the number of SNPs tested) P values as well as P values corrected with all performed tests (tot corrected) are shown. The analyses were performed using variables adjusted for potential confounding factors (age, body mass index, presence of any preoperative chronic pain condition, and anxiety score).