Fig. 2.
Effect of Lactobacillus rhamnosus GG and Bifidobacterium longum treatment on bacteremia in sepsis. Bacterial growth on representative Trypticase soy agar plates with sheep blood (5%) are shown for each experimental group (A, B). Septic mice had increased bacteremia (C) compared with shams (4.39 ± 0.56 vs. 0.40 ± 0.81; P = 0.0001), whereas septic mice treated with L. rhamnosus GG (LGG) or B. longum (BL) had reduced bacterial load in the blood (1.07 ± 1.54, P = 0.0001 and 2.70 ± 1.89, P = 0.016, respectively). Shams, n = 8 per group; septic, n = 10; LGG, n = 7; and BL, n = 8. Data are expressed as the mean ± SD. CFU = colony forming unit.