Fig. 4.
Mean number of TUNEL-positive cells (+SD) per counted brain region. There was a significant increase in TUNEL-positive cells in the NTIso group (positive control group) in all brain regions (cortex [P < 0.001], putamen [P = 0.003], hippocampus [P < 0.001], thalamus [P < 0.001], and white matter [P = 0.001]). Asterisks indicate a significance level of P < 0.05. HTXeFe = 24-h ventilation with 50% xenon and iv fentanyl at hypothermia; NTCTR = juvenile controls at normothermia; NTFe = 24-h iv fentanyl at normothermia; NTIso = 24-h ventilation with isoflurane at normothermia; NTXeFe = 24-h ventilation with 50% xenon and iv fentanyl at normothermia; TUNEL = terminal deoxynucleotidyl transferase–mediated deoxyuridine-triphosphate nick-end labeling.