Fig. 4. Receiving operating characteristics (ROC) curves of initial blood lactate (A ), and lactate clearance (B , LCcorrected[see Methods for explanation]). P values refer to the comparison of the area under the ROC curve versus 0.50 (i.e ., no discrimination). The dotted line corresponds to the nondiscrimination curve. Bootstrap analysis (1,000 random populations) was performed to obtain average ROC curves and box plot. AUC = area under curve.