Fig. 5.
Representative time courses to all events (i.e., the blue areas of fig. 4) from a posterior region of the hippocampus that were greater for the dexmedetomidine than the placebo condition are shown (A). For this same voxel (B), parsing the data into remembered and forgotten events revealed no significant subsequent memory effects. A representative blood oxygen level- dependent response from the common subsequent memory effect area (i.e., the green areas of fig. 4) shows that the dexmedetomidine and placebo responses were essentially identical when collapsed across all event types (C). However, parsing the data into remembered and forgotten events (D) revealed that a significant subsequent memory effect was present for both placebo and dexmedetomidine. A representative signal from the interaction subsequent memory effect area (i.e., the red areas of fig. 4) shows that the dexmedetomidine and placebo responses did not significantly differ across all events (E). However, parsing the data into remembered and forgotten events (F) reveals a much larger subsequent memory effect for placebo than dexmedetomidine. BOLD = blood oxygen level-dependent; DEX = dexmedetomidine; SME = subsequent memory effect.