Fig. 8. Effect of incision on miR-203 and phospholipase A2 activating protein (PLAA) mRNA levels in PPT-A null mutant (PPT-A −/−) mice and neurokinin-1 antagonist LY303870-treated mice after incision. Incision induced less down-regulation of miR-203 level (A and C ) and less up-regulation of PLAA mRNA level (B and D ) in PPT-A −/−mice and LY303870-treated group compared with wild-type mice and vehicle-treated group, respectively. Values are displayed as the mean ± SEM. For parameters measured in PPT-A −/−mice, n = 5; for all the other groups, n = 6. *P < 0.05, **P < 0.01, or ***P < 0.001 versus wild-type group or vehicle-treated group. miR-203 = microRNA 203; mRNA = messenger RNA; PLAA = phospholipase A2 activating protein; PPT = preprotachykinin-A gene knockout; WT = wild-type.