Fig. 5. Isoboles for 50% probability of tolerance to shaking and shouting (thick solid line ), tetanic stimulation (dotted line ), laryngeal mask airway insertion (thin solid line ), and laryngoscopy (dashed line ) for the Reduced Greco model, Minto model, Scaled C50^OHierarchical model, and Fixed C50^OHierarchical model. Note that the isoboles of tolerance to shaking and shouting and tetanic stimulation are almost the same for the Reduced Greco, Scaled C50^OHierarchical, and Fixed C50^OHierarchical models, and that the isoboles of tolerance to laryngeal mask airway insertion and laryngoscopy are almost the same for the Minto model.