Fig. 2. The mean arterial pressure (MAP) (A ), heart rate (HR) (B ), and cardiac output (CO) (C ) as hemodilution progresses to 6% hematocrit. Fio2= fraction of inspired oxygen. †P < 0.05 compared with baseline, §P < 0.05 compared with 29% hematocrit, ¶P < 0.05 compared with 18% hematocrit, and ‡P < 0.05 compared with 11% hematocrit.