Fig. 1. Exercise training reverses nerve injury–induced sensory hypersensitivity. (A ) Tactile paw withdrawal threshold in exercise-trained (EXC) versus sedentary animals (SED) that underwent spinal nerve ligation (SNL). Data from sham–operated on animals are included for comparison. (B ) Thermal paw withdrawal latency to radiant heat in EXC versus SED animals that underwent SNL. Data from sham–operated on animals are included for comparison. Baseline measurements were taken 1 day before surgery. Further measurements were performed 1 day before and weekly after the initiation of exercise training. Measurements were made 23 h after exercise. Data are given as mean (95% two-tailed CI). *P < 0.05 compared with EXC (rats) that underwent SNL. n = 6 animals per group. BL = presurgical baseline.