Fig. 3. Transient aortic occlusion (7.5 min) with mild systemic hypothermia (33°C) causes consistent but delayed hind limb locomotor deficits. Analysis of open-field locomotor function using the Basso Mouse Scale (BMS) reveals two functionally distinct cohorts of mice (i.e. , those that develop mild vs. severe neurological impairment). See Results for detailed description of the functional attributes that define these cohorts. Data are presented as mean (± SEM) BMS score as a function of days after ischemia/reperfusion.