Fig. 3. Xenon (xe) provides neuroprotection when applied up to 3 h after oxygen-glucose deprivation (OGD). The bars show the protective effect of 50% atm xenon applied immediately after OGD (0 h) and 3 and 6 h after OGD. The greatest degree of protection was observed when xenon was applied immediately (32 ± 6% of the control injury), but significant protection was observed even when xenon was applied 3 h after OGD (57 ± 12%). Sham slices were not exposed to OGD but received the same treatment and number of solution exchanges as the OGD slices. The error bars are standard errors from an average of 57 slices at each condition. The data have been normalized to the control OGD. * Significantly different (P < 0.05) from control OGD.