Fig. 6. Stored leukodepleted packed cells (erythrocytes [RBCs]) increase MADB106 lung tumor retention in operated rats more than in nonoperated rats. Percentage of lung tumor retention (mean ± SEM) in rats undergoing or not undergoing surgery and transfused with stored leukodepleted packed cells (RBCs) or with saline. Surgery significantly increased percentage of lung tumor retention, and blood transfusion further increased it, causing a significantly greater impact in operated than in nonoperated animals. * Significant pairwise difference from the no surgery saline group (protected least significant difference,  P < 0.05). ** Larger effect of RBC transfusion in animals undergoing surgery, compared with no surgery animals (analysis of variance interaction,  P < 0.05). n = 44; 7–9 in no surgery groups, 14–16 in surgery groups.