Fig. 6. (A ) Representative sections of immunostaining for hypoxia-inducible factor-1α in the penumbral cortex in sham, control (CON), and 30 μg/kg orexin-A (OXA) treatment groups. (B ) Quantitative analysis of the integrated optical density (IOD). Data are presented as mean ± SD. Scale bar, 20 μm. #P < 0.05 versus sham. *P < 0.05 versus control.