Fig. 2. Correlation of l-cysteine adduction reaction rate (t ½) in vitro with total duration of action (recovery of twitch to 95% of control height) of gantacurium, CW 002, and CW 011 at approximately 4–5 × ED95in anesthetized monkeys. R 2= 0.4883 (P < 0.0001). Twitch of the extensor digitorum was elicited at 0.15 Hz.