Fig. 6. Influence of barium sulfate pretreatment on methoxyflurane renal effects. Results are mean ± SD (controls n = 8, barium sulfate treated n = 10). Each set of five bars represents the preanesthetic sample and days 1–4 after methoxyflurane anesthesia. * Significantly different from premethoxyflurane sample ( P < 0.05). ** Significantly different from methoxyflurane controls ( P < 0.05). BUN = blood urea nitrogen.