Fig. 5. Impairment of urinary excretion rate related to the magnitude of hemorrhage. Filled symbols show the ratio between CL R2 from the two hemorrhage sessions and CL R1 from the fluid infusion-only experiment for each animal related to bleeding as a fraction of blood volume. The relationship can be described as an inhibitory Imax-function. The steepness of the curve is related to the exponential parameter (γ). Different γ values are displayed around the mean bleeding fraction that reduced renal excretion by 50%.