Fig. 2. Midazolam at 0.01 μm has no detectable effect on spontaneous inhibitory postsynaptic currents (sIPSCs). Recording from a cell showing a lack of effect of 0.01 μm midazolam on the decay time course (  A and  B ) and amplitude (  C ) of sIPSCs. All data are from the same cell. (  A ) Time series plot of 63% decay time measured for approximately 4,500 sIPSCs recorded for 15 min in control solution followed by 40 min in midazolam. (  B ) Probability distribution (  column plots ) and cumulative probability function (  line plots ) of 63% decay times (t^Decay) in control (  gray bars, solid line ) and midazolam (  hatched bars, dashed lines ). (  C ) Probability distribution (  column plots ) and cumulative probability function (  line plots ) of spontaneous inhibitory postsynaptic currents peak amplitude in control (  gray bars, solid line ) and midazolam (  hatched bars, dashed lines ).