Fig. 2. Effect of isoflurane on the time course for recovery of mechanical work during Langendorff (LR) and working (WR) reperfusion. Left ventricular minute work (LV work) values are shown for time control hearts (n = 13); untreated stored hearts (n = 20); hearts treated with isoflurane during the initial 10-min Langendorff perfusion (L) phase, the storage (S) phase, and Langendorff reperfusion (LR) phase (n = 15); isoflurane preconditioned hearts (n = 7); and isoflurane-preconditioned hearts treated with 5-hydroxydecanoate (5-HD) during storage (n = 6). *P < 0.05 versus  untreated stored hearts and isoflurane-preconditioned hearts treated with 5-HD during storage. Data are mean ± SEM.