Fig. 3. Enflurane exerted equal depressant actions on population-evoked responses in spinal cords from +/+ and −/− mice. (A and B ) Areas of the excitatory postsynaptic potential (EPSP) and slow ventral root potential (sVRP). (C and D ) Amplitudes of the dorsal root potential (DRP) early peak (point of maximum upward deflection) and late steady state (measured 1 s after the stimulus). Enflurane was applied during the time shown by the bar. Enflurane concentrations were approximately 0.7 MAC for pEPSP, 0.18 MAC for sVRP, and 0.7 MAC for DRP. None of the responses displayed a significant difference in sensitivity to enflurane between wild-type and mutant cords. Data points are means of four to five individual experiments, and error bars are SEM.