Figure 2. Effect of exposure to halothane on influx of²²Na in alveolar type II cells. Cells were exposed to halothane (concentration of 1% for 45 min). During this time, cells were depleted in a Na-free medium. At the end of exposure, influx of²²Na was measured in the presence of 1 mM ouabain to block the efflux of²²Na through Na,K-ATPase in the presence or absence of 100 [micro sign]m amiloride. Data represent the means +/- SD of six experiments done in triplicate. *Significantly different from the control value (P < 0.01).