Figure 5. Effects of L-NAME or methylene blue on strychnine- and bicuculline-induced allodynia. Strychnine (open circle, 0.25 micro gram) or bicuculline (closed circle, 1.25 micro gram) was injected simultaneously with various doses of L-NAME (A) or methylene blue (B) into the subarachnoid space. Assessment of allodynia was made as described in materials and methods. *0.01 less or equal to P < 0.05, **P < 0.01, as compared with strychnine- or bicuculline-injected group.