Figure 5. The effects of isoflurane and sevoflurane on the amplitude and the time constant of inactivation (tau^f) in peak amplitude of Calcium sup 2+ current (I^Ca). The reduction (%) of tau^fwas plotted against the reduction (%) of amplitude of I^Cacurrent produced by isoflurane (1.25, 2.5, 5.0 vol%; circles) and sevoflurane (2.5, 5.0 vol%; squares). The data of I^Cawere estimated at +20 mV. The anesthetic concentrations (vol%) are indicated above each symbol. Symbols represent mean+/-SEM; n = 6-10.