Fig. 2. Analysis of indocyanine green (ICG) dilution trace used to derive circulating blood volume (BVICG). Mixing of the ICG dye in the circulating blood volume was considered complete after three circulation times (3 ×ΔTcirc). ΔTcircwas estimated from the duration between the first pass peak and the maximum of the recirculation hump. Texpmarks the beginning of the exponential approximation. Estimated injection time T0precedes the first pass peak by ΔTcirc/2 s.