Fig. 1.
Schematic overview of animal experiments. The blood samples were collected before trauma induction and 12, 30, 60, 120, 180, and 240 min postinjury. Treatments included control group, 12.5 U/kg prothrombin complex concentrate (PCC), 25 U/kg PCC, 50 U/kg PCC, 12.5 U/kg PCC plus tranexamic acid, and 12.5 U/kg PCC plus tranexamic acid and fibrinogen concentrate.