Fig. 8.
Cardiomyocyte Ca2+ transient (ΔCai) depression and subsequent up-regulation after challenge with 4 μg/g of lipopolysaccharide (LPS). Average ΔCai (A), Ca2+ rise velocity (ΔCai/dt; B), time constant of Ca2+decay (τCa; C), Cai transient time to peak (D), and diastolic Cai levels (E) at baseline, 12 h after LPS administration, at day 3, and at day 6. Data are shown as mean ± SD. N = 37 cells from seven mice at baseline (37/7), 17/2 for 12 h, 39/3 for day 3, and 14/2 for day 6. BL = baseline; r.u. = ratiometric units. *P < 0.05 versus baseline.