Fig. 1.
Group analysis on power distribution of subthalamic nucleus firing. (A) Microelectrode recording revealed similar pattern of normalized root mean square values of raw subthalamic nucleus spike firing from both general anesthesia (n = 10) and local anesthesia (n = 9) groups of patients. Both groups have higher normalized root mean square values within subthalamic nucleus (0 to approximately 100%, dorsal to approximately ventral subterritory) compared with presubthalamic nucleus (less than 0%) and postsubthalamic nucleus (greater than 100%) depth recording. Shaded color area represents SD in each group. (B) Power ratio from individual frequency bands are compared between local anesthesia (n = 9) and general anesthesia (n = 10) groups and dorsal and ventral subthalamic nucleus subterritories. Power of beta band over dorsal subthalamic nucleus was significantly higher than over ventral subthalamic nucleus, and power of gamma band over ventral subthalamic nucleus was significantly higher than dorsal subthalamic nucleus in the local anesthesia group. These power differences in oscillation in topography were not found in the general anesthesia group. Conversely, subbeta band power (delta, theta, and alpha) was significantly higher in the subthalamic nucleus under sevoflurane general anesthesia. Single asterisk (*) indicates a significant difference of power between groups of designated bands with P value < 0.001. Double asterisks (**) indicate a significant difference between subterritories with P value < 0.001.