Fig. 3.
Local and interregional coherence during wakefulness, loss of consciousness (LOC), anesthesia, and return of consciousness (ROC). (A) Channel-to-channel local field potential coherence shown in the matrix for within and between the primary somatosensory cortex (S1), secondary somatosensory cortex (S2), and ventral premotor area (PMv) during wakefulness (for the last 1 min of awake performance), at LOC (for the first 1 min after LOC), during anesthesia (for the last 1 min of ketamine infusion), and at ROC (for the first 1 min after ROC). The matrices are shown for the slow-delta (0.5 to 4 Hz), theta (4 to 7 Hz), alpha (7 to 12 Hz), low beta (12 to 18 Hz), high beta (18 to 30 Hz), and gamma frequency band (30 to 65 Hz). (B) Statistical significance of the coherence change between wakefulness and LOC, anesthesia, or ROC (post hoc Bonferroni multiple comparisons for each channel-to-channel coherence). Significant increase (P < 0.05) is shown with red pixels, and significant decrease (P < 0.05) is shown with blue pixels.