Average electroencephalogram power of different frequency bands from frontal (F3, F4, top), central (C3, C4, middle), and occipital (O1, O2, bottom) electroencephalogram recordings from 20 volunteers. Remimazolam infusion is depicted as a gray horizontal bar. Time in relation to start of remimazolam administration. LOC, average loss of consciousness; ROC, average regain of consciousness.