Fig. 6.
The survival of R163C mice is enhanced by expression. Kaplan–Meier survival curves reveal that expression of dominant transient receptor potential canonical 6 (TRPC6) statistically significantly increased the mice survival time in RYR1-p.R163C mice from 15.3 ± 3 min to 35.5 ± 5 min RYR1-p.R163C/dominant-negative TRPC6. Seven mice per genotype. The values are expressed as means ± SD for each condition. Statistical analysis was done using a Mantel–Cox log rank test. *P ≤ 0.05.

The survival of R163C mice is enhanced by expression. Kaplan–Meier survival curves reveal that expression of dominant transient receptor potential canonical 6 (TRPC6) statistically significantly increased the mice survival time in RYR1-p.R163C mice from 15.3 ± 3 min to 35.5 ± 5 min RYR1-p.R163C/dominant-negative TRPC6. Seven mice per genotype. The values are expressed as means ± SD for each condition. Statistical analysis was done using a Mantel–Cox log rank test. *P ≤ 0.05.

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