Fig. 5.
Comparison of propofol-induced spike synchrony among pyramidal neurons responding to presynaptic fast-spiking neuron activation at 1 (A), 4 (B), 6.7 (C), 10 (D), and 13.3 Hz (E). Two pyramidal neurons (pyramidal neuron 1 and pyramidal neuron 2) received inhibitory input from a fast-spiking neuron. Pyramidal neurons showed termination of spike firing in response to the first spike induction in the fast-spiking neuron at all ranges (arrowheads); however, subsequent spike synchrony was observed only in the case in which the fast-spiking neuron was activated at 6.7 and 10 Hz under application of propofol.