Isoflurane suppresses local field potentials recorded in the hippocampal cornu ammonis 1 subfield in vivo. (A) Representative traces of raw local field potentials (0.1 to 500 Hz) recorded in hippocampal cornu ammonis 1 region for control or isoflurane (0.5%). (B) Power spectrogram of raw cornu ammonis 1 showing isoflurane effect. (C) Power spectral density of raw local field potentials for control or isoflurane. Representative traces (D), power spectrogram (E), and power spectral density (F) of delta frequency band (0.1 to 4 Hz). Representative traces (G), power spectrogram (H), and power spectral density (I) of theta frequency band (4 to 12 Hz). Representative traces (J), power spectrogram (K), and power spectral density (L) of ripple frequency band (100 to 200 Hz). Solid lines represent mean values, and shaded regions represent 95% CI. Data were analyzed by a two-tailed paired t test (C, F, I, and L; n = 9/group; 5/4 males/females).