Fig. 5. The concentration–time relation of rocuronium for one individual patient for the whole experiment. The straight line represents the fit with the recirculatory model, and the dashed line represents the fit with the two-compartmental model. (Inset ) The concentration–time relation is shown for the same patient for the first 4 min after bolus injection, and the measured concentrations that were used for the compartmental fit are left open. Note that samples collected during the first 20 s contained no or very small (< 10 ng/ml) concentrations of rocuronium and are therefore not shown.