Joinpoint analysis for (A) missing unused medications (two intercepts and three slopes), (B) no kit returned (zero intercepts and one slope), and (C) missing witness signatures (zero intercepts and one slope). The number of intercepts was determined using the Bayesian Information Criteria values as determined by the Joinpoint software. Transitions between pre-Controlled Substance Management Application (CSMA) period, the implementation period, and the post-CSMA period are indicated with red lines. The slopes for each segment are presented in the figure in units of errors/month.