Adjunctive Glucocorticoid Therapy in Patients with Septic Shock (ADRENAL)–Activated Protein C and Corticosteroids for Human Septic Shock (APROCCHSS): Probability of survival and risk of death at 90 days, according to subgroup. Shown are the Kaplan–Meier estimates of the probability of survival for patients receiving either hydrocortisone or placebo. The P value was calculated using a Cox proportional hazard model including the randomized treatment arm, admission type, and a random-center effect. HR, hazard ratio.