Fig. 5.
Anesthesia causes significant hypoacetylation of histone-3 (h3) in the immature hippocampus. Anesthesia causes significant hypoacetylation at lysine residue 14 of histone-3 at 2 h (A; n = 7 to 8, *P = 0.042) and at 24 h as compared with age-matched controls (B; n = 9, **P = 0.005). GA = general anesthesia.