Fig. 3.
Least-squares mean (standard error [SE]) area under the curve (AUC) of numeric rating scale (NRS) pain scores at rest during three successive 24-h periods (0 to 24, 24 to 48, and 48 to 72 h) after total knee arthroplasty for subjects receiving liposome bupivacaine 266 mg (blue bars) or placebo (red bars) in study part 2. All between-group differences were statistically significant (*P < 0.0083).