Fig. 7.
The effect of postnatal age on cortical oscillatory activity after C-fiber electrical hind paw skin stimulation. Time– frequency decomposition of the evoked somatosensory cortical neural activity at each isoflurane step at postnatal day (P) 7, P14, P21, and P30. The time–frequency energy changes, time locked to each C-fiber stimulus, are presented as a group median (10 stimuli per animal, n = 7 animals). Results are displayed as increases and decreases of energy changes relative to a baseline period of 1 s before stimulation. Energy values between 0 and −2 correspond to energy decreases, whereas the values between 0 and 2 correspond to energy increases (n = 7 animals for each age group).