Fig. 4.
Effects of sodium thiosulfate (STS) on IκB/nuclear factor-κB (NFκB) signaling pathway. Levels of total and phosphorylated inhibitor of NFκB (p-IκB) and p65 subunit of NFκB normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in lung tissue homogenates 24 h after challenge with saline or lipopolysaccharide (LPS). ***P < 0.001, **P < 0.01, *P < 0.05; two-way ANOVA Bonferroni posttest, mean ± SD. Numbers in bars represent the sample size. p65 = p65 subunit of NFκB.

Effects of sodium thiosulfate (STS) on IκB/nuclear factor-κB (NFκB) signaling pathway. Levels of total and phosphorylated inhibitor of NFκB (p-IκB) and p65 subunit of NFκB normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in lung tissue homogenates 24 h after challenge with saline or lipopolysaccharide (LPS). ***P < 0.001, **P < 0.01, *P < 0.05; two-way ANOVA Bonferroni posttest, mean ± SD. Numbers in bars represent the sample size. p65 = p65 subunit of NFκB.

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