Fig. 1.
Effects of sodium thiosulfate (STS) on lipopolysaccharide (LPS)-induced or polymicrobial sepsis-induced lung injury. (A) Total number of leukocytes and (B) polymorphonuclear neutrophils (PMNs) in bronchoalveolar lavage fluid. (C) Myeloperoxidase (MPO) levels and (D) total protein concentration in bronchoalveolar lavage fluid. (E) Mouse lung wet dry ratio. (F, G) Inflammatory cytokine levels in bronchoalveolar lavage fluid. (H) Interleukin (IL)-6 levels in mouse lung subjected to cecal ligation and puncture (CLP). ***P < 0.001, **P < 0.01, *P < 0.05; (A–D, F, G) two-way ANOVA Bonferroni posttest, (E, H) one-way ANOVA Bonferroni posttest, mean ± SD. Numbers in bars represent the sample size. SO = sham operation; TNFα = tumor necrosis factor-α.