Fig. 4.
Gene expression in acute lung inflammation animals. Data are presented as mean ± SD. Comparisons among groups were performed using one-way ANOVA. Messenger RNA (mRNA) expressions of genes are normalized to the respective housekeeping gene (glycerylaldehyde-3-phosphate dehydrogenase). (A) interleukin-6 (IL-6); (B) caspase 3; (C) receptor of advanced glycation end-products (RAGE); (D) surfactant protein B (SP-B); (E) type III procollagen (PC III); (F) vascular cell adhesion molecule-1 (VCAM-1); (G) intercellular cell adhesion molecule-1 (ICAM-1). CT = threshold cycle; I:E = inspiratory-to-expiratory; lipopolysaccharide-NV = nonventilated animals with acute lung inflammation; MV = mechanical ventilation; STPhigh = high levels of stress versus time product (I:E 2:1); STPlow = low level of stress versus time product (I:E 1:2); STPmid = middle level of stress versus time product (I:E 1:1).