(A) Dose-dependent effect of neostigmine on postoperative hospital length of stay. Postoperative hospital length of stay was significantly longer in patients who received high-dose neostigmine (2.9 days [95% CI, 2.7–3.2] vs. 2.8 days [95% CI, 2.8–2.9], P = 0.032, ordinal regression analysis). (B) Dose-dependent effect of neostigmine on time to postanesthesia care unit (PACU) discharge readiness. Time until PACU discharge readiness was significantly longer in patients who received high-dose neostigmine (176 min [95% CI, 165–188] vs. 157 min [95% CI, 153–160], P = 0.011, ordinal regression analysis). *Significant findings.