Fig. 7.
Changes in expression of phosphorylated cyclic adenosine monophosphate–response element–binding protein (pCREB) after intraperitoneal administration of midazolam in postnatal days 28 rats. A, B, and C (upper panels: ×4 magnification; lower panels: ×20 magnification) are photomicrographs of pCREB immunostaining in the hippocampal CA3 area from postnatal days 28 rats. D, E, and F (upper panels: ×4 magnification; lower panels: ×20 magnification) are those of pCREB immunostaining in the thalamus from postnatal days 28 rats. G and H show the number of pCREB-positive cells (mm2) in the hippocampal CA3 area and thalamus, respectively. MDZ = midazolam. **P < 0.01. Data are derived from 12 slices in each group.

Changes in expression of phosphorylated cyclic adenosine monophosphate–response element–binding protein (pCREB) after intraperitoneal administration of midazolam in postnatal days 28 rats. A, B, and C (upper panels: ×4 magnification; lower panels: ×20 magnification) are photomicrographs of pCREB immunostaining in the hippocampal CA3 area from postnatal days 28 rats. D, E, and F (upper panels: ×4 magnification; lower panels: ×20 magnification) are those of pCREB immunostaining in the thalamus from postnatal days 28 rats. G and H show the number of pCREB-positive cells (mm2) in the hippocampal CA3 area and thalamus, respectively. MDZ = midazolam. **P < 0.01. Data are derived from 12 slices in each group.

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