Effect of neonatal anesthesia on wakefulness. (A ) Neonatal anesthesia did not affect the total amount of time spent awake in Anesthesia 2h animals compared with sham-controls (P = 0.067). (B ) The average number of wake bouts per hour was unchanged in Anesthesia 2h rats compared with sham-controls (P = 0.776). (C ) The mean duration of wake bouts per hour was also unchanged in Anesthesia 2h rats compared with sham-controls (P = 0.669). N = 11 sham-control and 10 Anesthesia 2h rats.